General Products

PHARMA THIRD PARTY CONTRACT MANUFACTURER OF ACECLOFENAC & THIOCOLCHICOSIDE

Introduction


This is the combination of NSAID & muscle relaxant where Aceclofenac plays the role of a non-steroidal anti-inflammatory product with analgesic, & antiarthritic action & Thiocolchicoside plays a major role in relaxing the muscles during spasms. 

Class

NSAID & Muscle Relaxant

Mechanism of action  

 Thiocolchicoside antagonizes the action of GABA-A receptor and thereby prevent the body from spasticity by reducing spasms. Aceclofenac function is to reduce inflammation which is possible by the reduction in prostaglandin which can occur by the inhibition of cyclooxygenase enzyme. 

Pharmacokinetic

Absorption-rapidly absorbed 

Bioavailability of Aceclofenac-100% 

Bioavailability of Thiocolchicoside-25%

Protein binding of Aceclofenac -99%

Protein binding of Thiocolchicoside-12.8%

A half-life of Aceclofenac -4 hours

A half-life of Thiocolchicoside-3.2-7 hours

Excretion-Urinary excretion 

Pharmacological Uses

The combination is used in the painful spasm of musculoskeletal and neuromuscular. It may be used for post-operative pain, shoulder pain, knees pain, and acute low back pain. 

Side Effects

Blurred vision & anxiety 

Hypertension

Muscle cramps 

Elevation in hepatic enzymes 

Dizziness & vertigo 

Abdominal discomfort 

product Interactions

The products are as follow which interferes with the action of this combination are Acemetacin which can produce side effects and by Chlorthalidone decreases therapeutic effects of this combination. Other examples are Citric acid, Atenolol, and caffeine. 

Dosage

As per the recommendation of a doctor or pharmacist. 

We are the supplier of Aceclofenac & Thiocolchicoside also a trader of Aceclofenac & Thiocolchicoside.

*The following symptoms are suggestive & needs to be confirmed before promoting or coating anywhere & anybody whom so ever. Power2pharma.com & its parent company NEWS pharma Pvt. Ltd. is not responsible for its authenticity.

 


ACECLOFENAC 100mg, THIOCOLCHICOSIDE 4mg Tablet ALU-ALU 10*10