PHARMA THIRD PARTY CONTRACT MANUFACTURER OF ACECLOFENAC & THIOCOLCHICOSIDE
This is the combination of NSAID & muscle relaxant where Aceclofenac plays the role of a non-steroidal anti-inflammatory product with analgesic, & antiarthritic action & Thiocolchicoside plays a major role in relaxing the muscles during spasms.
NSAID & Muscle Relaxant
Mechanism of action
Thiocolchicoside antagonizes the action of GABA-A receptor and thereby prevent the body from spasticity by reducing spasms. Aceclofenac function is to reduce inflammation which is possible by the reduction in prostaglandin which can occur by the inhibition of cyclooxygenase enzyme.
Bioavailability of Aceclofenac-100%
Bioavailability of Thiocolchicoside-25%
Protein binding of Aceclofenac -99%
Protein binding of Thiocolchicoside-12.8%
A half-life of Aceclofenac -4 hours
A half-life of Thiocolchicoside-3.2-7 hours
The combination is used in the painful spasm of musculoskeletal and neuromuscular. It may be used for post-operative pain, shoulder pain, knees pain, and acute low back pain.
Blurred vision & anxiety
Elevation in hepatic enzymes
Dizziness & vertigo
The products are as follow which interferes with the action of this combination are Acemetacin which can produce side effects and by Chlorthalidone decreases therapeutic effects of this combination. Other examples are Citric acid, Atenolol, and caffeine.
As per the recommendation of a doctor or pharmacist.
We are the supplier of Aceclofenac & Thiocolchicoside also a trader of Aceclofenac & Thiocolchicoside.
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