Antibiotics Products

PHARMA THIRD PARTY CONTRACT MANUFACTURER OF CEFIXIME & OFLOXACIN

Introduction


This combination of active products Cefixime & Ofloxacin shows broad-spectrum antibiotic. The synergistic action of both these products gives a better patient compliance. Cefixime is a third generation cephalosporin used against extended-spectrum beta-lactamase (ESBL) whereas Ofloxacin is associated with the group of antimicrobials that is fluoroquinolones & they are active against H.influenzae & S.pneumoniae.

Class

Cefixime is a Third Generation Cephalosporin Antibiotic & Ofloxacin is the Second-Generation Fluoroquinolones class. 

Mechanism of action

The procedure of working of Cefixime & Ofloxacin to prevent from bacterial infection is different from each other however the target of both these products is to protect the body against bacteria. Cefixime works by inhibiting the cell wall synthesis of bacteria & stop their growth & Ofloxacin works by restricting the synthesis of the nucleic acid of bacteria.

Pharmacokinetic

Pharmacokinetics of this product are-

Absorption of Cefixime trihydrate-40-50%

Absorption of Ofloxacin-approx. 98%

Distribution- Cefixime trihydrate-protein binding is 65%

The half-life of Ofloxacin-9 hours 

Rate may be decreased if taken with food. It crosses the placenta. 

Excretion-60% Non-renal

Pharmacological uses of Cefixime & Ofloxacin 

The combination of Cefixime & Ofloxacin is used in various types of infections as Urinary Tract Infection (UTI), Typhoid fever, Skin Infection, Bone & Joint Infection, Eye & Ear Infection, Sexually transmitted & respiratory infection, chronic bronchitis exacerbation & Gonorrhea

Side Effects of Cefixime & Ofloxacin

Dry Mouth

Diarrhea

Abdominal pain

Dizziness

Insomnia

Dyspepsia 

product Interaction with Cefixime & Ofloxacin

Rifampin

Rifabutin

Dosage 

The dose recommended is 200 mg/day twice a day or consult with your pharmacist. 

We are the supplier of Cefixime & Ofloxacin & also a trader of Cefixime & Ofloxacin.

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CEFIXIME 100mg, OFLOXACIN 100mg Tablet ALU-ALU 10*10