Antibiotics Products

PHARMA THIRD PARTY CONTRACT MANUFACTURER OF CEFUROXIME AXETIL & CLAVULANIC ACID

Introduction


Cefuroxime Axetil when administered into the body after its metabolization the active form being formed. It is a cephalosporin antibiotic of the second generation on the contrary potassium clavulanate (Clavulanic acid) beta-lactamase inhibitor is added to support the therapeutic action. 

Class

Cephalosporin and beta-lactamase inhibitor

Mechanism of action

Cefuroxime Axetil work to kill the bacteria from its root completely by targeting the cell wall of bacteria as others beta-lactam do so. Potassium clavulanate/clavulanic acid is itself a beta-lactamase inhibitor although it has less antimicrobial activity but is added in this combination to prevent the destruction of Cefuroxime.

Pharmacokinetics

Bioavailability- Cefuroxime-67.9%

The serum half-life of cefuroxime is -1.2 hours.

Protein binding is 50%, rapidly hydrolyzed

Half-Life-1.2 hours

Pharmacological Uses

The Cefuroxime Axetil and clavulanic acid in combination are prescribed to the patients with 

Respiratory tract infections, Otitis media

Pharyngitis, Sinusitis, Bronchitis

Urinary Tract Infections (UTI)

Lyme disease & Impetigo

Side Effects

If not taken accurately as prescribed following side effects may lead to the body like Nausea, Vomiting, Epidermal necrosis, Anaphylaxis, Nephrotoxicity, Jarisch-Herxheimer Reaction, Accumulation of gas and Dizziness & drowsiness. 

product Interactions

Antacids (rabeprazole, omeprazole, pantoprazole)

Oral contraceptives

Probenecid decreases renal clearance of Cefuroxime. 

Dosage

As per the recommendation. 

We are the supplier of Cefuroxime Axetil and clavulanic acid & also a trader of Cefuroxime Axetil and clavulanic acid.

* The following symptoms are suggestive & needs to be confirmed before promoting or coating anywhere & anybody whom so ever. Power2pharma.com & its parent company NEWS pharma Pvt. Ltd. is not responsible for its authenticity.

 


CLAVULANIC ACID 125mg, CEFUROXIME AXETIL 250mg Tablet ALU-ALU 10*1*10