PHARMA THIRD PARTY CONTRACT MANUFACTURER OF CEFUROXIME AXETIL & CLAVULANIC ACID
Cefuroxime Axetil when administered into the body after its metabolization the active form being formed. It is a cephalosporin antibiotic of the second generation on the contrary potassium clavulanate (Clavulanic acid) beta-lactamase inhibitor is added to support the therapeutic action.
Cephalosporin and beta-lactamase inhibitor
Mechanism of action
Cefuroxime Axetil work to kill the bacteria from its root completely by targeting the cell wall of bacteria as others beta-lactam do so. Potassium clavulanate/clavulanic acid is itself a beta-lactamase inhibitor although it has less antimicrobial activity but is added in this combination to prevent the destruction of Cefuroxime.
The serum half-life of cefuroxime is -1.2 hours.
Protein binding is 50%, rapidly hydrolyzed
The Cefuroxime Axetil and clavulanic acid in combination are prescribed to the patients with
Respiratory tract infections, Otitis media
Pharyngitis, Sinusitis, Bronchitis
Urinary Tract Infections (UTI)
Lyme disease & Impetigo
If not taken accurately as prescribed following side effects may lead to the body like Nausea, Vomiting, Epidermal necrosis, Anaphylaxis, Nephrotoxicity, Jarisch-Herxheimer Reaction, Accumulation of gas and Dizziness & drowsiness.
Antacids (rabeprazole, omeprazole, pantoprazole)
Probenecid decreases renal clearance of Cefuroxime.
As per the recommendation.
We are the supplier of Cefuroxime Axetil and clavulanic acid & also a trader of Cefuroxime Axetil and clavulanic acid.
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