General Products

PHARMA THIRD PARTY CONTRACT MANUFACTURER OF ETORICOXIB

Introduction-


Etoricoxib an NSAID (Non-steroidal anti-inflammatory product) is a second-generation cyclooxygenase-2 inhibitor. This is an efficacious alternative in the management of arthritis & pain. Etoricoxib is a selective cyclooxygenase (COX)-2 inhibitors. Currently, etoricoxib is approved in more than 60 countries worldwide.

Class Cyclooxygenase-2 (COX-2) selective NSAIDs

Mechanism of Action

Etoricoxib exhibits a greater selectivity for cox-2 (Cyclo-oxygenase) over cox-1. COX-2 is an enzyme which is responsible for the inflammation & pain at the injury’s site. Etoricoxib inhibits the action of COX-2 which reduces the prostaglandins (PGs) generation from arachidonic acid.

Pharmacokinetics

Etoricoxib is 83% absorbed (incompletely).

Etoricoxib bioavailability is 100%      

Etoricoxib has a long half-life (approx 20-26 hrs)

Etoricoxib bound to plasma proteins-92%

Etoricoxib Metabolized by a Hepatic mechanism 

Etoricoxib has a rapid onset time & long duration of action.                                    

Pharmacological uses

Etoricoxib can be prescribed for the Symptomatic relief in the treatment of Osteoarthritis, Rheumatoid Arthritis, Acute Gouty Arthritis, Muscular skeletal pain, and Post-operative pain & in Primary Dysmenorrheal, Ankylosing spondylitis, chronic low back pain etc.

Side Effects of Etoricoxib                             

The adverse effects can be increased when Aceclofenac is combined with etoricoxib. Acetylsalicylic acid is combined with etoricoxib.

Nausea

Vomiting

Erythema

Acute generalized exanthematous pustulosis

product Interaction-                                   

Etoricoxib may increase the anticoagulant activities of Abciximab. 

The serum concentration of etoricoxib can be increased when it is combined with Abiraterone.

It may reduce plasma levels with rifampicin.

Dosage

Etoricoxib tablet contains 30mg, 60mg, 90mg, 120mg Etoricoxib & the recommended dose is one tablet per day or as recommended by your pharmacist.

We are the supplier of Etoricoxib & also a trader of Etoricoxib.

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ETORICOXIB 90mg Tablet ALU-ALU 10*10