PHARMA THIRD PARTY CONTRACT MANUFACTURER OF LEVOCETIRIZINE, PHENYLEPHRINE, CAFFEINE & PARACETAMOL
The combination of these three active products is designed in order to avoid the individual administration of these products. This is the perfect combination of an antihistaminic product that is Levocetirizine used against the allergic symptoms, an analgesic & antipyretic product that is Paracetamol for pain & fever management & a Decongestant that is Phenylephrine used to remove the blockage in airways. Caffeine (Methylxanthine) is associated with this group of CNS Stimulant.
Class Antihistamine, Analgesic & Antipyretic, Decongestant
Mechanism of Action
The therapeutic action of Paracetamol as an analgesic can be seen by elevating the pain threshold & anti-pyretic effect by blocking the effects produced by endogenous pyrogen. Phenylephrine action is an agonist of the Alpha-1-adrenergic receptor & Levocetirizine works by the cut off the histamine binding to the receptor which is essential for allergy. Caffeine works to stimulate respiratory center for vasoconstriction & increases respiratory rate.
Absorption of combination-Rapidly (oral)
Bioavailability of Phenylephrine-38%
Protein binding of Levocetirizine-91-92%
Protein binding of Paracetamol- 25%
Protein binding of Phenylephrine-95%
Protein binding of Caffeine-25-36%
A half-life of Levocetirizine-8-9 hours
A half-life of Paracetamol -1-4 hours
A half-life of Phenylephrine-2.1-3.4 hours
A half-life of Caffeine-3-7 hours
The fusion of Levocetirizine, Paracetamol, and Phenylephrine may be prescribed for the prevention of various illness like allergic disorder, dust & pet allergies, swelling on the skin, Ear-round allergies, fever, & pain, Ear pain, joint pain, Headache & also used as a nasal decongestant.
Itching & redness
The products which may interact with this combination are
Clotrimazole (decreases metabolism)
Alcohol & laboratory tests
For a dose, recommendation consults with your doctor or pharmacist (healthcare professional).
We are the supplier Levocetirizine, Paracetamol, Caffeine and Phenylephrine & also a trader of Levocetirizine, Paracetamol, Caffeine, and Phenylephrine.
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