General Products

CONTRACT MANUFACTURER OF LEVOCETIRIZINE & MONTELUKAST 

Introduction


This is the effective combination for the prevention & treatment of allergic rhinitis. Levocetirizine produced from the Cetirizine belongs to the third generation Antihistamine products of non-sedating action. Montelukast Sodium is classified as an antagonist of leukotriene receptor which is used to get relief from asthma & decreases bronchoconstriction. 

Class Antihistamine & leukotriene antagonist

Mechanism of Action

Levocetirizine functioning can be understood by its inhibition on the binding of histamine on the histamine-1 receptor to block the histamine action. Montelukast works to prevent airway edema by its antagonistic action that is by inhibiting leukotriene D4 at its binding site which cysteinyl leukotriene receptor is resulting in contraction of smooth muscle. 

Pharmacokinetics

Absorption of product-Rapidly (oral)

Protein binding of Levocetirizine-91-92%

Protein binding of Montelukast-99%

The half-life of Levocetirizine-8-9 hours 

The half-life of Montelukast-2.7-5.5 hours 

Pharmacological Uses 

The combination of Levocetirizine HCl & Montelukast sodium is used in the inflammation of the nose, Allergic rhinitis, and Exercise-induced bronchospasm prevention, for asthma control, chronic idiopathic urticaria & obstructive airways disease. 

Side Effects

A Sore throat

Nausea & Diarrhea

Abdominal pain

Indigestion or stomach upset 

Dizziness

Painful urination

Vision problems 

product Interaction 

Amiodarone (its serum concentration increases)

Theophylline

Ritonavir

Alcohol

Dosage

Each tablet contains 2.5mg of Levocetirizine HCl & 5mg of Montelukast. For dose recommendation kindly consult with your Doctor or Pharmacist.

We are the supplier of Levocetirizine HCl & Montelukast sodium & also a trader of Levocetirizine HCl & Montelukast sodium.

*The following symptoms are suggestive & needs to be confirmed before promoting or coating anywhere & anybody whom so ever. Power2pharma.com & its parent company NEWS pharma Pvt. Ltd. is not responsible for its authenticity.



 


MONTELUKAST SODIUM 10mg, LEVOCETIRIZINE 5mg Tablet ALU-ALU 10*10