PHARMA THIRD PARTY CONTRACT MANUFACTURER OF LEVOCETIRIZINE & MONTELUKAST
Levocetirizine produced from the Cetirizine, belongs to the third generation Antihistamine products of non-sedating action. Montelukast Sodium is classified as an antagonist of leukotriene receptor which is used to get relief from asthma & decreases bronchoconstriction.
They are the antagonist of histamine & leukotriene
Mechanism of action
Levocetirizine Antihistaminic action can be seen by its inhibition on the binding of histamine on the histamine-1 receptor to block the histamine action. Montelukast works by its antagonistic action on leukotriene D4 at its binding site which cysteinyl leukotriene receptor is resulting in contraction of smooth muscle.
The plasma protein binding of Levocetirizine and Montelukast is 91-92% and 99%.
The Half-life of Levocetirizine and Montelukast 8-9 hours and 2.7-5.5 hours.
Excretion of the combination is observed in urine.
Allergic rhinitis- This is the main area of its prescription by the mostly healthcare professional to treat all the allergic symptoms related itching, watery eyes, sneezing etc.
Dosage-As per doctor suggestion.
We are the supplier of Levocetirizine HCl & Montelukast sodium & also a trader of Levocetirizine HCl & Montelukast sodium.
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