General Products

PHARMA THIRD PARTY CONTRACT MANUFACTURER OF ACECLOFENAC & THIOCOLCHICOSIDE

Introduction


This is an effective combination of a muscle relaxer and an anti-inflammatory compound. As both these products are completely efficacious in their work and their synergistic action gives you a complete relief with a longer shelf life. 

Class

These products are the members of NSAID & Muscle Relaxant group. 

Mechanism of action

Thiocolchicoside antagonizes the action of GABA-A receptor and thereby prevent the body from spasticity by reducing spasms. Aceclofenac function is to reduce inflammation which is possible by the reduction in prostaglandin which can occur by the inhibition of cyclooxygenase enzyme. 

Pharmacokinetic

The combination absorbed rapidly in the gastrointestinal tract. The Bioavailability of Aceclofenac is 100% and Thiocolchicoside is 25%. With the Protein binding of 99% of Aceclofenac and 12.8% of Thiocolchicoside. The Half-life of Aceclofenac & Thiocolchicoside 4 hours and 3.2-7 hours. 

Pharmacological Uses

Painful spasm of musculoskeletal 

Neuromuscular spasm

Post-operative pain

Shoulder & knees pain 

Acute low back pain

Side Effects

This combination is associated with several adverse reactions which are as follow 

Blurred vision & anxiety, Hypertension, Muscle cramps, Elevation in hepatic enzymes, Dizziness & vertigo and abdominal discomfort. 

product Interactions

Amrubicin (its excretion rate decreases) 

Atenolol (its anti-hypertensive action decreases) 

Chlorthalidone (therapeutic effects decreases) 

Dosage

The most commonly prescribed dosage is one tablet twice a day or per advice. 

We are the supplier of Aceclofenac & Thiocolchicoside also a trader of Aceclofenac & Thiocolchicoside.

*The following symptoms are suggestive & needs to be confirmed before promoting or coating anywhere & anybody whom so ever. Power2pharma.com & its parent company NEWS pharma Pvt. Ltd. is not responsible for its authenticity.

 


THIOCOLCHICOSIDE 8mg, ACECLOFENAC 100mg Tablet ALU-ALU 10*10