PHARMA THIRD PARTY CONTRACT MANUFACTURER OF ACECLOFENAC & THIOCOLCHICOSIDE
This is an effective combination of a muscle relaxer and an anti-inflammatory compound. As both these products are completely efficacious in their work and their synergistic action gives you a complete relief with a longer shelf life.
These products are the members of NSAID & Muscle Relaxant group.
Mechanism of action
Thiocolchicoside antagonizes the action of GABA-A receptor and thereby prevent the body from spasticity by reducing spasms. Aceclofenac function is to reduce inflammation which is possible by the reduction in prostaglandin which can occur by the inhibition of cyclooxygenase enzyme.
The combination absorbed rapidly in the gastrointestinal tract. The Bioavailability of Aceclofenac is 100% and Thiocolchicoside is 25%. With the Protein binding of 99% of Aceclofenac and 12.8% of Thiocolchicoside. The Half-life of Aceclofenac & Thiocolchicoside 4 hours and 3.2-7 hours.
Painful spasm of musculoskeletal
Shoulder & knees pain
Acute low back pain
This combination is associated with several adverse reactions which are as follow
Blurred vision & anxiety, Hypertension, Muscle cramps, Elevation in hepatic enzymes, Dizziness & vertigo and abdominal discomfort.
Amrubicin (its excretion rate decreases)
Atenolol (its anti-hypertensive action decreases)
Chlorthalidone (therapeutic effects decreases)
The most commonly prescribed dosage is one tablet twice a day or per advice.
We are the supplier of Aceclofenac & Thiocolchicoside also a trader of Aceclofenac & Thiocolchicoside.
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