Cardiac/Diabetic Products

PHARMA THIRD PARTY CONTRACT MANUFACTURER OF VOGLIBOSE

Introduction


Voglibose is an oral antihyperglycemic product which is an alpha-glucosidase inhibitor prescribed for a patient with diabetes mellitus (Type-2, Non-insulin dependent diabetes) for lowering post-prandial blood glucose level.

Class Anti-diabetic or Antihyperglycemic

Mechanism of action

Voglibose works by inhibiting alpha-glucosidase inhibitors. These are the enzymes which are mandatory for the digestion of carbohydrates. Oligosaccharides, trisaccharides, and disaccharides hydrolyzed to glucose and other monosaccharides in the small intestine by membrane-bound intestinal alpha-glucosidases.

Pharmacokinetics

Absorption-slowly & poorly absorbed

Metabolism of Voglibose-By intestinal enzyme & microbial flora

Excretion- Excreted in Urine & feces

Pharmacological Uses

Voglibose may be prescribed for the treatment of Diabetes, Reduces blood glucose level thereby prevents Kidney damage, and Blindness, Nerve problems & Sexual function problems & Loss of limbs. It also decreases the risk of macrovascular complications.

Side Effects

Constipation

Feeling of discomfort

Blurred vision

Abdominal pain

Flatulence

Abnormal liver function

Nausea, vomiting or diarrhea

product Interactions

Chlorthalidone (will decrease efficacy)

Lipoic acid (increase hypoglycemic activity)

Methyclothiazide (will decrease efficacy)

Pregabalin (risk of heart-failure decrease)

Contraindicated in breastfeeding, hypersensitivity & diabetic coma.

Dosage-

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VOGLIBOSE 0.2mg Tablet ALU-ALU 10*10